Takeshi Ota

11:25 Ying Swan Ho
Metabolomics-Based Approaches to Drive the Development of Optimal Biotherapeutics Production Processes and the Unravelling of Disease Mechanisms
11:55 Tomoya Kinumi
Reference material: Tool for traceable measurement and characterization of monoclonal antibody
12:10 Naoki Kawase
Multi Attribute Method for antibody therapeutics
12:25 Takeshi Ota
Utilizing of Antigens with Uniformed N-linked Glycans Facilitate Epitope Analysis of Glycoproteins via HDX-MS

Organized by Susumu Uchiyama (The University of Osaka, Japan) and Nana Kawasaki (Yokohama City University, Japan)
Nowadays, pharmaceuticals are not only traditional small-molecule drugs, but are also being developed in a variety of ‘modalities’, such as proteins, nucleic acids, protein complexes and nucleic acid-lipid complexes, which have complex structures and large molecular weights, and the manufacturing methods have also diversified to include chemical synthesis, biotechnology and combinations thereof. Mass spectrometry, on the other hand, is an indispensable analytical technique regardless of modality, from production to quality analysis of formulations and even post-administration pharmacokinetics. In two sessions of this annual meeting, several pharmaceutical modalities that have emerged in recent years will be introduced and discussed, with examples of research on each modality and the role played by mass spectrometry.